李浩轩，浙江大学“百人计划”研究员，国家青年海外高层次引进人才，博士生导师。主要从事 DNA 与 RNA 表观遗传修饰在植物生长发育及产量形成中的调控机制研究。以水稻和拟南芥为模式系统，系统绘制 RNA 修饰图谱，致力于解析其在翻译调控与发育过程中的动态作用机制。
相关研究成果以第一作者或通讯作者（含共同）身份发表在Nature Plants、Cell Research、Nature Communications、Plant Biotechnology Journal、Trends in Plant Science、New Phytologist 和Plant Physiology 等国际期刊。
教育及研究经历：
2008.09–2012.06 南京农业大学，农学，本科
2012.08–2017.11 香港中文大学，生物学，博士
2017.11–2022.09 香港中文大学/香港浸会大学，博士后
2022.09–2025.02 美国芝加哥大学，博士后
2025.03–2026.03 美国芝加哥大学，Research Scientist
2026年至今 浙江大学，“百人计划”研究员
团队与招生
课题组聚焦植物表观遗传调控前沿问题，结合多组学技术与分子生物学手段，探索 RNA 修饰在生命过程中的功能与机制。团队致力于营造开放、专注且具有探索精神的科研环境。
诚挚欢迎对植物分子生物学、表观遗传学及生物信息学感兴趣的博士生、博士后加入，共同开展具有挑战性与创造性的研究工作。
近5年发表的论文
†co-first authors, *corresponding authors
(1) Li, H. †, Li, X. †, He, Kayla. †, Dang, H., Shen, W., Zhang, P., He, C. & Wang, G. (2026). KAS-seq captures global transcription dynamics and active single-stranded enhancers in rice. Plant Biotechnology Journal, accept.
(2) Li, H. †, Li, X. †, Zhang, J. & Wang, G. (2025). The light-responsive chromatin accessibility landscape in rice. Plant Physiology, 2025 Oct, 199.2: kiaf438.
(3) Li, T., Huang, J., Wang, G.*, Li, H.*, Lü, P*. (2025). Regulatory roles of RNA modifications in plant development and fruit ripening. aBIOTECH, 2025 Aug, 8:1-7.
(4) Xin, T., Zhang, Z., Zhang, Y., Li, X., Wang, S., Wang, G., Li, H., Wang, B., Zhang M., Tang, W., He., C., Huang, S. & Yang, X. (2025). Recessive epistasis of a synonymous mutation confers cucumber domestication through epitranscriptomic regulation. Cell, 2025 July, p4517-4529.e15.
(5) Li, H., Wang, G., Ye, C., Zou, Z., Jiang, B., Yang, F., He, K., Ju, C., Zhang, L., Gao, B., Liu, S., Chen, Y., Zhang, J. & He, C. (2025). Quantitative RNA pseudouridine maps reveal multi-layered translation control through plant rRNA, tRNA and mRNA pseudouridylation. Nature Plants, 2025 Feb, 11:234-247.
(6) Wang, G.†, Li, H.†, Ye, C.†, He, K., Liu S., Jiang B., Zhang, J. & He, C. (2024). Quantitative profiling of m6A at single base resolution across the life cycle of rice and Arabidopsis. Nature Communications, 2024 Jun, 15(1): 4881.
(7)Wang, G. †, Shen, W. †, Huang, M., Zhang, J*. & Li, H.* (2022). The chromatin accessibility landscape of pistil and anther development in rice. Plant Physiology, 2022 Dec, 190(4): 2797-2811.
(8) Li, H., You, C., Yoshikawa, M., Yang, X., Gu, H., Li, C., Cui, J., Chen, X., Ye, N., Wang, G. & Zhang, J. (2022). A spontaneous thermo-sensitive female sterility mutation in rice endows full mechanized hybrid breeding. Cell Research, 2022 Oct, 32(10):931-945.
(9)Li, H., Li, X., Wang, G., Wang, G. & Zhang, J. (2022). Analysis of Gene Expression in Early Seed Germination of Rice: Landscape and Genetic Regulation. BMC Plant Biology, 2022 Feb, 22(1): 1-14.
(10)Li, H., Li, A., Shen, W., Ye, N., Wang, G. & Zhang, J. (2021). Global Survey of Alternative Splicing in Rice by Direct RNA Sequencing During Reproductive Development: Landscape and Genetic Regulation. Rice, 2021 Dec, 14(1), 75.
(11) Li, H., Li, A., Shen, W., Zhang, J. & Wang, G. (2021). Use of NAD-Seq to Profile NAD+-Capped RNAs in Plants. Trends in plant science, 2021 Aug, 26(8):871-2.
(12)Wang, G., Li, X., Ye, N., Li, H.* & Zhang, J*. (2021). OsTPP1 regulates seed germination through the crosstalk with abscisic acid in rice. New Phytologist, 2021 Jun, 230(5): 1925-1939.
(13)Wang, G., Li, X., An, Y., Zhang, J*. & Li, H.* (2021). Transient ChIP-seq for Genome-wide in vivo DNA Binding Landscape. Trends in Plant Science, 2021 May, 26(5):524-5.
